I setup one of my hotbars with all the Runecrafting combo's when I lvled it. I thought I had posted this a long time ago, but I guess not. Im sure someone else has had the same idea, but its not posted. Anyway, here it is.
I seperated all the hotkeys in the chat with blank spaces(my name with nothing next to it). On the hotbar itself, it shows what each list is. Either RC(crystals), +5(totems), +10(totems), ++10(multi-orb totems), Regen(totems), Mob(pet totems), and Rune(Rune combo's).
Hope this helps.
*EDIT*
Didnt relize that chat was a little hard to read in that picture. So I'll type it.
Hotbar setup: F1 = RC; F2 = RC; F3 = RC; F4 = +5; F5 = +10; F6 = ++10; F7 = Resist; F8 = Regen; F9 = Mob; F10 = Mob; F11 = Rune; F12 = Rune
F1: Red Crystal - 2 garnet, 1 hematite
Green Crystal - 1 topaz, 1 amethyst
Blue Crystal - 1 garnet, 2 blue topaz
Yellow Crystal - 2 topaz, 2 garnet
F2: Sky Crystal - 2 diamond, 3 sapphire
Dark Crystal - 2 black pearl, 2 hematite
Crimson Crystal - 2 ruby, 3 pearl
Twisted Crystal - 1 diamond, 3 amethyst
F3: Metallic Crystal - 2 emerald, 3 topaz
Spectral Crystal - 2 ruby, 3 sapphire
Water Crystal - 3 sapphire, 1 diamond
Glowing Crystal - 2 diamond, 2 sapphire
F4: Triddle Strength - 2 green, 2 red - Str
Bear's Will - 2 blue, 2 yellow - Con
Nimble Kobold - 2 red, 2 blue - Dex
Mental Clarity - 2 green, 2 yellow - Int
F5: Troll Strength - 3 red, 1 sky - Str
Giants Will - 2 sky, 1 dark - Con
Alacrity - 2 green, 2 dark - Dex
Brilliance - 3 blue, 2 crimson - Int
F6: Warrior - 3 red, 2 dark, 1 crimson - Str, Con
Mage - 3 blue, 2 crimson, 2 twisted - Int, Con
Archer - 2 sky, 1 dark, 1 crimson - Str, Dex
Battlemage - 1 g/r/b/y, 2 metallic - Str, Int
F7: Druid - 3 green, 1 sky - Nature
Wizard - 3 blue, 1 sky - Mind
Necromancer - 3 yellow, sky - Soul
Cleric - 3 red, 2 crimson - Body
F8: Hardiness - 3 green, 1 twisted - Stam
Regeneration - 2 green/red/twisted - Hp, Stam
Stamina Return - 2 green/red/metallic - Stam
Burst - 1 spectral, 2 water, 3 glowing - Speed
F9: Bat - 3 crimson, 1 twisted, 2 spectral
Rat - 4 dark, 1 spectal, 1 water
Termigon - 3 spectral, 2 glowing
Undead Wolf - 4 spectral, 2 water
F10: Hound - 4 spectral, 1 glowing
F11: Red - Body; Green - Nature; Blue - Mind
Yellow - Soul; Sky - Malith; Dark - Malenox
Crimson - Agon; Twisted - Sabal
Metallic - Veldan; Spectral - Kuthos
F12: Water - Ulthien; Glowing - Isos/Adregard
Well, there ya go! Its all pretty self-explanatory. Any questions, just ask.